Heartburn can increase the risk of developing esophageal cancer. This is due to the backwash of stomach acids damaging the esophageal lining, which can cause cell changes that can lead to caner.

It is recommended to drink a minimal amount of coffee and citrus juices. It is also a good idea to cut back on spicy foods to control heart burn. H2 blockers, such as Zantac, and proton pump inhibitors, such as Prilosec, can help to reduce symptoms and encourage the healing of damaged tissues.

http://healthvoice.blogspot.com/2008/07/heartburn-can-lead-to-esophageal-caner.html